Django handles requests using a request-response cycle.
When a user makes a request to a Django application, the request is routed to the appropriate view, which is a Python function that handles the request and returns a response. The view then interacts with the model, which is a layer of code that interacts with the database to retrieve or store information. Finally, the view renders a template, which is a HTML file with placeholders that are filled in with data from the model.
For example, if a user makes a request to view a list of products, the request is routed to a view that interacts with the model to retrieve the list of products from the database. The view then renders a template that contains the list of products, which is then sent back to the user as a response.